How does HCG Diet work for weight loss?
The main way that HCG is affecting weight loss is by stimulating the production of estrogen, progesterone, and testosterone, in both males and females. The latter hormone, being an anabolic steroid, is largely responsible for the results of HCG treatment. Testosterone, for example, acts to build muscle which is why it is a hormone that has been used for bodybuilding. However, in small amounts, it counteracts the catabolism, or "breakdown", of bodily tissues during a state of starvation.
Combined Effort. Dr Morunga works in partnership with Adri Ferreira Nutritionist and Registered Naturopath to formulate a plan that is tailored specifically to your needs. A full dietary program is undertaken including baseline measurements of current nutritional status, body composition and goals to be achieved. Following your assessment and implementation of the program you will be reviewed weekly during the course of treatment to ensure your goals are met.
Chemistry - HCG is a gonad-stimulating polypeptide secreted by the placenta. It occurs as a white or practically white, amorphous, lyophilized powder. It is soluble in water and practically insoluble in alcohol. One International Unit of HCG is equal to one USP unit. There are at least 1500 USP Units per mg. Chorionic gonadotropin has many synonyms, including human chorionic gonadotropin, HCG , hCG , CG , chorionic gonadotrophin , pregnancy-urine hormone , and PU .
Storage/Stability/Compatibility - Chorionic gonadotropin powder for injection should be stored at room temperature (15-30°C) and protected from light. After reconstitution, the resultant solution is stable for 30-90 days (depending on the product) when stored at 2-15°C.
Pharmacology - HCG mimics quite closely the effects of luteinizing hormone (LH), but also has some FSH-like activity. In males, HCG can stimulate the differentiation of, and androgen production by, testicular interstitial (Leydig) cells. It may also stimulate testicular descent when no anatomical abnormality is
present. In females, HCG will stimulate the corpus luteum to produce progesterone, and can induce ovulation.
Mechanism HCG is an analog for many hormone precursors in the body. This means it stimulates the thyroid, ovaries (in females), testes (in males), and adrenal glands, as well as other tissues in the body that are affected by hormone levels. The main way that HCG is affecting weight loss is by stimulating the production of estrogen, progesterone, and testosterone, in both males and females. The latter hormone, being an anabolic steroid, is largely responsible for
the results of HCG treatment. Testosterone, for example, acts to build muscle which is why it is a hormone that has been used for bodybuilding. However, in
small amounts, it counteracts the catabolism, or "breakdown", of bodily tissues during a state of starvation.
This acts to preserve muscle tissue during dieting. This preservation of muscle tissue is so important because by preventing its break down we preserve metabolism and lean body structure including muscle tone. This may be why people who claim to lose weight with HCG claim to lose weight differently than with standard weight loss regimens.
In standard regimens there is a loss of fat and muscle with an overall shrinking of body size. With an HCG regimen, people claim to undergo a re-shaping
of their body and removal of certain fat deposits. The evidence for this unique change in shape after HCG use with diet is not in the mere weight loss, but in
the fact that it is unique that HCG allows for selective fat loss and the sparing of muscle to produce a change in body composition, which produces a
change in shape of the body.
Therefore, HCG is not a magic injection. It does not cause weight loss by itself. In fact, the only way to lose a significant amount on HCG is to adhere to a diet regimen of calorie restriction, which is implemented at the outset.
Pharmacokinetics - HCG is destroyed in the GI tract after oral administration, so it must be given parenterally. After IM injection, peak plasma levels occur
in about 6 hours. HCG is distributed primarily to the ovaries in females and to the testes in males, but some may also be distributed to the proximal tubules in
the renal cortex. HCG is eliminated from the blood in biphasic manner. The initial elimination half-life is about 11 hours and the terminal half-life is approximately 23 hours.
Contraindications HCG is contraindicated in patients with
1. Prostatic Carcinoma
2. Breast cancer
3. Ovarian Cancer
4. Can overly stimulate the ovaries, called ovarian hyper stimulation syndrome, contraindicated with history of ectopic pregnancy or a multiple birth
5. Uterine Cancer
6. Thyroid Disorder
7. Adrenal Disorder
8. Hypothalamus and Pituitary Disease Disorders
9. Other Androgen-dependent Neoplasia
10. Precocious puberty
11. Previous hypersensitivity reaction to HCG.
Safety Yes HCG has an excellent safety profile. Large amounts of HCG are released during pregnancy without any harmful side effects. The amount of HCG used in weight loss programs is only a fraction of what is naturally released in pregnancy. Antibody production to this hormone has been reported after repetitive use, resulting in diminished effect.
Precautions May have increased risk of a multiple births if get pregnant on HCG. Men with gynecomastia,, should avoid injecting HCG because it can cause
further swelling and enlargement.
Adverse Effects/Warnings - Pain at the injection site, gynecomastia, headache, depression, irritability and edema.
Overdosage - No overdosage cases have been reported with HCG.
Drug Interactions - No interactions have apparently been reported with HCG.
Note that clinical results may vary depending on individual factors, including medical history, client compliance with pre-post treatment instructions and individual response to treatment.